Also known as nocturnal pruritus itching skin at night is a common condition these days. There can be natural as well as health related causes behind it. Your skin functions like fluid balance temperature regulation and barrier protection get influenced by your body s natural circadian rhythms. And these functions slightly change at night making you feel itchy. Also your body releases more cytokines at night which is responsible for increasing inflammation. Sometimes dry skin is the reason behind itchy feeling. Apart from these causes there are certain health conditions including liver disease thyroid problems psychological conditions nerve disorders allergic