Turns out Tobacco use remains a leading cause of oral cancer but the tobacco landscape is evolving with increasing use of non-cigarette tobacco products and dual-use of multiple product types. Participants were categorized according to use of combustible which includes cigarettes cigars water pipe pipes blunts (marijuana-containing cigars) smokeless which includes moist snuff chewing tobacco and snus e-cigarettes and nicotine replacement products. For each product the recent use was defined as within the prior three-days and non-use defined as none within 30-days. All tobacco use categories demonstrated elevated nicotine and tobacco-specific nitrosamines (TSNAs) concentrations relative to non-users. TSNA exposures were