Researchers have identified a drug that can significantly reduce bone and cartilage progression in osteoarthritis. In a study published in the journal Annals of Internal Medicine the researchers found that MIV-711 -- a novel selective cathepsin K inhibitor -- can reduce disease progression in osteoarthritis. However the drug was not more effective than placebo for reducing pain related to knee osteoarthritis. Osteoarthritis of the knee is a painful disabling condition affecting more than 14 million people in the US and hundreds of millions worldwide. The pain of knee osteoarthritis arises from a series of pathologic processes involving articular cartilage subchondral
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